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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT3
All Species:
26.06
Human Site:
Y346
Identified Species:
47.78
UniProt:
O60678
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60678
NP_005779.1
531
59903
Y346
S
M
L
D
S
V
L
Y
A
K
N
K
Y
L
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092890
531
59784
E346
N
I
I
T
S
M
A
E
T
K
N
Y
F
A
G
Dog
Lupus familis
XP_534089
541
60618
Y356
S
M
L
D
S
V
L
Y
A
K
N
K
Y
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q922H1
532
59884
Y343
S
M
L
D
S
V
L
Y
A
K
S
K
Y
L
A
Rat
Rattus norvegicus
O70467
528
59401
Y343
S
M
L
D
S
V
L
Y
A
K
S
K
Y
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505718
571
63850
Y386
S
M
L
D
S
V
I
Y
A
K
S
K
Y
L
T
Chicken
Gallus gallus
XP_420907
526
59430
Y341
S
M
L
D
S
V
I
Y
A
K
D
K
Y
L
A
Frog
Xenopus laevis
Q8AV13
369
42306
F190
L
T
P
D
G
L
I
F
P
D
R
A
T
L
Y
Zebra Danio
Brachydanio rerio
Q5RGQ2
419
48204
F240
L
K
P
G
G
F
M
F
P
D
R
A
T
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396035
525
60169
Y342
G
M
L
D
T
V
I
Y
A
R
D
N
Y
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192186
519
58632
V334
L
E
D
L
D
M
P
V
E
K
S
I
F
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82210
366
41153
L187
L
V
D
G
G
I
V
L
P
D
K
A
S
L
Y
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
H169
F
P
D
K
C
S
I
H
L
A
G
L
E
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.1
90.9
N.A.
89.8
89.2
N.A.
78.8
70.8
35.4
35.7
N.A.
N.A.
42.5
N.A.
45
Protein Similarity:
100
N.A.
96.8
95.1
N.A.
93.9
93.9
N.A.
85.9
83.2
49.1
52.3
N.A.
N.A.
62.5
N.A.
63.6
P-Site Identity:
100
N.A.
20
100
N.A.
93.3
93.3
N.A.
80
86.6
13.3
6.6
N.A.
N.A.
53.3
N.A.
6.6
P-Site Similarity:
100
N.A.
53.3
100
N.A.
100
100
N.A.
93.3
100
33.3
20
N.A.
N.A.
80
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.1
31.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
54
8
0
24
0
8
39
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
24
62
8
0
0
0
0
24
16
0
0
8
0
% D
% Glu:
0
8
0
0
0
0
0
8
8
0
0
0
8
0
0
% E
% Phe:
8
0
0
0
0
8
0
16
0
0
0
0
16
0
0
% F
% Gly:
8
0
0
16
24
0
0
0
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
8
39
0
0
0
0
8
0
0
0
% I
% Lys:
0
8
0
8
0
0
0
0
0
62
8
47
0
0
0
% K
% Leu:
31
0
54
8
0
8
31
8
8
0
0
8
0
77
0
% L
% Met:
0
54
0
0
0
16
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
24
8
0
8
0
% N
% Pro:
0
8
16
0
0
0
8
0
24
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
16
0
0
0
0
% R
% Ser:
47
0
0
0
54
8
0
0
0
0
31
0
8
0
16
% S
% Thr:
0
8
0
8
8
0
0
0
8
0
0
0
16
0
16
% T
% Val:
0
8
0
0
0
54
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
8
54
0
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _